Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ATP4A | P20648 | 7/20 | 0.51 |
| ▸ | ATP4B | P51164 | 7/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143838 | 0.84 | RAB9A (0.72) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5329073 | 0.82 | RAB9A (0.67) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7384847 | 0.81 | LTA4H (0.60) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7403707 | 0.80 | RAB9A (0.68) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1802368 | 0.80 | RAB9A (0.59) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2812807 | 0.75 | ALDH1A1 (0.52) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL127807 | 0.75 | RAB9A (1.00) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1887643 | 0.75 | MAPT (0.60) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11838315 | 0.74 | LTA4H (0.62) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1771825 | 0.74 | ALDH1A1 (0.79) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020177594-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-11-28 | — | — | US | disclosed |
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020177594-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC11, HDAC3 | RAB9A 2823/4885NPC1 285/4885MAPT 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.