Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356361 | 0.85 | PANK3 (0.39) | OGAHTR1AHTR7 | |
| SCHEMBL4809534 | 0.80 | MMP13 (0.39) | OGAAKT1MEN1KMT2AKDM4E | |
| SCHEMBL4814260 | 0.73 | OGA (0.38) | OGAAKT1KDM4EPKMHTR1A | |
| SCHEMBL7358595 | 0.71 | MMP7 (0.38) | OGAMEN1KMT2AKDM4EPKM | |
| SCHEMBL7362584 | 0.71 | GRM5 (0.35) | KDM4E | |
| SCHEMBL14252769 | 0.69 | CYP3A4 (0.48) | OGAKDM4E | |
| SCHEMBL7358015 | 0.67 | PANK3 (0.43) | OGAKMT2AHTR1AHTR7 | |
| SCHEMBL4816479 | 0.66 | MMP7 (0.51) | OGAKDM4EPKM | |
| SCHEMBL4813569 | 0.65 | SMO (0.50) | OGA | |
| SCHEMBL4814569 | 0.65 | MMP7 (0.46) | OGAHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109787-A1 | ARYLPIPERAZINES AND THEIR USE AS METALLOPROTEINASE INHIBITING AGENTS (MMP) | AstraZeneca AB (SE) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000012478-A1 | ARYLPIPERAZINES AND THEIR USE AS METALLOPROTEINASE INHIBITING AGENTS (MMP) | ASTRAZENECA AB (SE) | 2000-03-09 | — | — | WO | disclosed |