Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 8/20 | 0.53 |
| ▸ | CASP7 | P55210 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 12/20 | 0.53 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | CASP9 | P55211 | 1/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13444229 | 0.84 | CASP3 (0.46) | CASP3CASP7CASP1CASP8CASP6 | |
| SCHEMBL8247253 | 0.83 | CASP3 (0.67) | CASP3CASP1CASP8CASP6 | |
| SCHEMBL7745119 | 0.83 | CASP3 (0.67) | CASP3CASP1CASP8CASP6 | |
| SCHEMBL29802248 | 0.83 | CASP1 (0.54) | CASP3CASP7CASP1CASP8CASP6 | |
| SCHEMBL29802526 | 0.83 | CASP1 (0.54) | CASP3CASP7CASP1CASP8CASP6 | |
| SCHEMBL7364481 | 0.82 | CASP3 (0.62) | CASP3CASP7CASP1CASP9 | |
| SCHEMBL27057949 | 0.81 | CTSL (0.52) | CASP3CASP7CASP1CASP8CASP2 | |
| SCHEMBL7423249 | 0.80 | CASP1 (0.54) | CASP3CASP7CASP1 | |
| SCHEMBL20756235 | 0.80 | CTSL (0.54) | CASP3CASP7CASP1CASP8CASP2 | |
| SCHEMBL19275168 | 0.80 | CTSL (0.54) | CASP3CASP7CASP1CASP8CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611375-A1 | PEPTIDES INHIBITING IL-1 BETA RELEASE | SANDOZ LTD. (CH) | 1994-08-24 | — | — | EP | disclosed |
| WO-1993009135-A1 | PEPTIDES INHIBITING IL-1 BETA RELEASE | SANDOZ LTD. (CH) | 1993-05-13 | — | — | WO | disclosed |