Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | FADS1 | O60427 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365516 | 0.89 | FADS1 (0.47) | P2RX1FADS1PTGS1JAK2JAK1 | |
| SCHEMBL7365270 | 0.85 | ALDH1A1 (0.47) | P2RX1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL7367677 | 0.83 | NR1H4 (0.54) | RXFP1NPC1RAB9AALDH1A1 | |
| SCHEMBL7367977 | 0.79 | JAK2 (0.46) | P2RX1FADS1PTGS1JAK2JAK1 | |
| SCHEMBL7370255 | 0.74 | KMT2A (0.46) | P2RX1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL7368382 | 0.73 | NR1H4 (0.55) | RXFP1NPC1RAB9AALDH1A1 | |
| SCHEMBL7365818 | 0.72 | SCN3A (0.46) | P2RX1FADS1PTGS1RXFP1NPC1 | |
| SCHEMBL1780159 | 0.71 | NPC1 (0.37) | P2RX1FADS1PTGS1HSD17B10KDM4E | |
| SCHEMBL29851692 | 0.69 | ALDH1A1 (0.63) | HSD17B10KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL171563 | 0.69 | ALDH1A1 (0.63) | HSD17B10KDM4ENPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |