Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 16/20 | 0.54 |
| ▸ | PPARG | P37231 | 11/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368382 | 0.90 | NR1H4 (0.55) | NR1H4PPARGPPARAPPARDRXFP1 | |
| SCHEMBL7364732 | 0.83 | P2RX1 (0.43) | RXFP1NPC1ALDH1A1RAB9A | |
| SCHEMBL7373717 | 0.81 | NR1H4 (0.57) | NR1H4PPARGPPARAPPARDTP53 | |
| SCHEMBL6171509 | 0.80 | NR1H4 (0.63) | NR1H4PPARGPPARAPPARDTP53 | |
| SCHEMBL7365270 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1GLARAB9AL3MBTL1 | |
| SCHEMBL7370555 | 0.75 | NR1H4 (0.59) | NR1H4PPARGPPARAPPARDTP53 | |
| SCHEMBL6172308 | 0.74 | NR1H4 (0.64) | NR1H4PPARGPPARAPPARDRXFP1 | |
| SCHEMBL7365516 | 0.73 | FADS1 (0.47) | RXFP1NPC1ALDH1A1RAB9A | |
| SCHEMBL7368426 | 0.73 | NPC1 (0.54) | NR1H4PPARGPPARAPPARDRXFP1 | |
| SCHEMBL5226864 | 0.72 | NR1H4 (0.77) | NR1H4PPARGPPARAPPARDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |