Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191918 | 0.85 | TACR2 (0.51) | SMN1; SMN2KMT2ALMNAMEN1KDM4E | |
| SCHEMBL7367889 | 0.81 | HTT (0.57) | SMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7369353 | 0.81 | RAB9A (0.56) | SMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL5105512 | 0.77 | MEN1 (0.77) | SMN1; SMN2KMT2AMEN1CD274 | |
| SCHEMBL7370861 | 0.77 | TACR2 (0.56) | KMT2ALMNATACR2ALDH1A1MAPT | |
| SCHEMBL7369227 | 0.77 | QPCT (0.63) | SMN1; SMN2L3MBTL1KDM4EPOLBALDH1A1 | |
| SCHEMBL7286780 | 0.76 | L3MBTL1 (0.56) | SMN1; SMN2KMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL7375405 | 0.75 | BCHE (0.52) | — | |
| SCHEMBL7372543 | 0.74 | NPC1 (0.56) | SMN1; SMN2 | |
| SCHEMBL8472345 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2ALMNAMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | claimed |