Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369353 | 0.99 | RAB9A (0.56) | HTTRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL7370861 | 0.91 | TACR2 (0.56) | ALDH1A1EGFR | |
| SCHEMBL7371156 | 0.83 | HTT (0.57) | HTTRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL7365328 | 0.82 | NPC1 (0.56) | HTTRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL7341842 | 0.82 | NPC1 (0.56) | HTTRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL7364944 | 0.81 | SMN1; SMN2 (0.51) | KDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL7375405 | 0.80 | BCHE (0.52) | — | |
| SCHEMBL7372543 | 0.79 | NPC1 (0.56) | HTTRAB9ANPC1SMN1; SMN2LTA4H | |
| SCHEMBL10926918 | 0.78 | MEN1 (0.69) | HTTRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL7369242 | 0.78 | DPP7 (0.59) | HTTRAB9ANPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | claimed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |