SCHEMBL7375405

SCHEMBL7375405

NC(=O)C(C(=O)NCCNCc1ccccc1)c1ccc(OCc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCHE P06276 5/20 0.52
DPP7 Q9UHL4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7372543 0.90 NPC1 (0.56)
SCHEMBL7370246 0.81 DPP7 (0.57) BCHEDPP7
SCHEMBL7373073 0.80 TDP1 (0.53)
SCHEMBL7367889 0.80 HTT (0.57)
SCHEMBL7369353 0.79 RAB9A (0.56)
SCHEMBL5099006 0.78 PDCD1 (0.65) BCHE
SCHEMBL7370861 0.78 TACR2 (0.56)
SCHEMBL15201156 0.77 NOX1 (0.60) BCHE
SCHEMBL7369227 0.75 QPCT (0.63)
SCHEMBL7368377 0.75 ALOX5 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998054123-A1 SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS WARNER-LAMBERT COMPANY (US) 1998-12-03 WO claimed
WO-1998054123-A1 SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS WARNER-LAMBERT COMPANY (US) 1998-12-03 WO disclosed