Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 3/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345393 | 0.87 | ITGB3 (0.46) | ITGB3ITGA2BNLRP3POLBACE | |
| SCHEMBL7341598 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BNLRP3POLBACE | |
| SCHEMBL7365261 | 0.82 | ITGB3 (0.47) | ITGB3ITGA2BFKBP1AALDH1A1TP53 | |
| SCHEMBL7342847 | 0.77 | ITGB3 (0.44) | ITGB3ITGA2BNLRP3ACEFKBP1A | |
| SCHEMBL7342258 | 0.73 | ITGB3 (0.45) | ITGB3ITGA2BACEALDH1A1TP53 | |
| SCHEMBL7371673 | 0.72 | ITGB3 (0.51) | ITGB3ITGA2BACEALDH1A1HRH3 | |
| SCHEMBL7342693 | 0.71 | ITGB3 (0.79) | ITGB3ITGA2BACEHRH3 | |
| SCHEMBL7369685 | 0.71 | ITGB3 (0.47) | ITGB3ITGA2BFKBP1AHTT | |
| SCHEMBL3288909 | 0.71 | HDAC1 (0.51) | ITGB3ITGA2BACE | |
| SCHEMBL6739005 | 0.71 | NLRP3 (0.49) | NLRP3POLBALDH1A1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866705-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0866705-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997014417-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-04-24 | — | — | WO | disclosed |