Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369685 | 0.88 | ITGB3 (0.47) | ITGB3ITGA2BGAAFKBP1AITGAV | |
| Hydrochloric Acid SCHEMBL7370233 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BGAAFKBP1AITGAV | |
| SCHEMBL7365263 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BFKBP1AALDH1A1CYP1A2 | |
| SCHEMBL8620491 | 0.79 | ITGB3 (0.35) | ITGB3ITGA2BGAAFKBP1AKMT2A | |
| SCHEMBL7448188 | 0.78 | ITGB3 (0.46) | ITGB3ITGA2BFKBP1AITGAVSLC1A2 | |
| SCHEMBL7338126 | 0.77 | ITGB3 (0.52) | ITGB3ITGA2BITGAVSLC1A2KCNA5 | |
| Hydrochloric Acid SCHEMBL7338692 | 0.76 | ITGB3 (0.51) | ITGB3ITGA2BITGAVSLC1A2KCNA5 | |
| Hydrochloric Acid SCHEMBL7348254 | 0.75 | GAA (0.35) | GAAOPRM1KCNA5NAMPTKMT2A | |
| SCHEMBL7342690 | 0.74 | ITGB3 (0.55) | ITGB3ITGA2BITGAVALDH1A1HSD17B10 | |
| SCHEMBL8617240 | 0.74 | ITGB3 (0.39) | ITGB3ITGA2BFKBP1AITGAVSLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866705-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0866705-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997014417-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-04-24 | — | — | WO | disclosed |