Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27162825 | 0.89 | KDM4E (0.42) | KDM4EPKMHPGDGPR119ALDH1A1 | |
| SCHEMBL20075951 | 0.89 | ALDH1A1 (0.44) | HPGDGPR119ALDH1A1 | |
| SCHEMBL7358506 | 0.89 | HPGD (0.46) | KDM4EPKMHPGDGPR119FAAH | |
| SCHEMBL8912276 | 0.85 | GPR119 (0.40) | KDM4EPKMHPGDGPR119ALDH1A1 | |
| SCHEMBL27162479 | 0.84 | NR1H2 (0.41) | KDM4EPKMHPGDGPR119ALDH1A1 | |
| SCHEMBL118661 | 0.84 | HPGD (0.48) | KDM4EHPGDGPR119ALDH1A1 | |
| SCHEMBL24481256 | 0.84 | CNR1 (0.41) | KDM4EPKMHPGDALDH1A1 | |
| SCHEMBL27007016 | 0.83 | HPGD (0.48) | KDM4EPKMHPGDGPR119ALDH1A1 | |
| SCHEMBL27314016 | 0.83 | KDM4E (0.41) | KDM4EPKMHPGDGPR119FAAH | |
| SCHEMBL7360145 | 0.83 | ALDH1A1 (0.42) | KDM4EPKMHPGDGPR119ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |