SCHEMBL8912276

SCHEMBL8912276

CC(C)(C)OC(=O)CN1CCC(N2CCN(CCC3CCN(C(=O)OC(C)(C)C)CC3)CC2)CC1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 7/20 0.40
KDM4E B2RXH2 1/20 0.39
PKM P14618 1/20 0.39
HPGD P15428 1/20 0.39
FAAH O00519 1/20 0.39
ALDH1A1 P00352 2/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
RECQL P46063 1/20 0.38
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7360145 0.93 ALDH1A1 (0.42) GPR119KDM4EPKMHPGDFAAH
SCHEMBL7368909 0.87 SMN1; SMN2 (0.43) GPR119KDM4EPKMHPGDFAAH
SCHEMBL7365403 0.85 KDM4E (0.41) GPR119KDM4EPKMHPGDFAAH
SCHEMBL7367257 0.82 KDM4E (0.47) GPR119KDM4EPKMHPGDFAAH
SCHEMBL7362773 0.81 CHRM4 (0.59) GPR119KDM4EPKMALDH1A1CHRM4
SCHEMBL24745481 0.80 HPGD (0.46) GPR119KDM4EHPGDALDH1A1CHRM1
SCHEMBL1795814 0.80 HPGD (0.46) GPR119HPGDALDH1A1CHRM1NPC1
SCHEMBL13713286 0.80 OPRM1 (0.42) ALDH1A1L3MBTL1
SCHEMBL27007016 0.80 HPGD (0.48) GPR119KDM4EPKMHPGDFAAH
SCHEMBL309857 0.79 HPGD (0.45) GPR119KDM4EHPGDALDH1A1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9110833-A None JP disclosed
JP-H09110833-A NEW PIPERIDINE DERIVATIVE OR ITS SALT YAMANOUCHI PHARMACEUT CO LTD 1997-04-28 JP disclosed