Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912276 | 0.93 | GPR119 (0.40) | ALDH1A1KDM4EPKMNPC1MAPT | |
| SCHEMBL7368909 | 0.91 | SMN1; SMN2 (0.43) | ALDH1A1KDM4EPKMNPC1MAPT | |
| SCHEMBL7365403 | 0.83 | KDM4E (0.41) | ALDH1A1KDM4EPKMGPR119HPGD | |
| SCHEMBL7340706 | 0.82 | GPR119 (0.51) | ALDH1A1EPHX1PTPN2PTPN1PTPN6 | |
| SCHEMBL31657251 | 0.81 | KDM4E (0.46) | ALDH1A1KDM4EPKMNPC1MAPT | |
| SCHEMBL25329388 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4EPKMNPC1MAPT | |
| SCHEMBL1207110 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4EPKMEPHX1PTPN2 | |
| SCHEMBL7367257 | 0.80 | KDM4E (0.47) | ALDH1A1KDM4EPKMNPC1MAPT | |
| SCHEMBL30737084 | 0.80 | NR1H2 (0.43) | ALDH1A1NPC1MAPTMAPK1HTT | |
| Hydrochloric Acid SCHEMBL8477692 | 0.80 | GNAO1 (0.40) | L3MBTL1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |