Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.41 |
| ▸ | JAK1 | P23458 | 3/20 | 0.41 |
| ▸ | CFTR | P13569 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ULK1 | O75385 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367697 | 0.87 | NR1H4 (0.45) | NAMPT | |
| SCHEMBL7367977 | 0.84 | JAK2 (0.46) | JAK2JAK1PTGS1FLT3ALDH1A1 | |
| SCHEMBL7364651 | 0.81 | NR1H4 (0.45) | NAMPT | |
| SCHEMBL7366495 | 0.81 | FLT3 (0.45) | JAK2JAK1FLT3ALDH1A1LMNA | |
| SCHEMBL7373717 | 0.81 | NR1H4 (0.57) | FLT3 | |
| SCHEMBL7366169 | 0.79 | FLT3 (0.43) | JAK2JAK1FLT3ALDH1A1LMNA | |
| SCHEMBL7368010 | 0.78 | FLT3 (0.46) | JAK2JAK1FLT3ALDH1A1LMNA | |
| SCHEMBL7368426 | 0.78 | NPC1 (0.54) | FLT3CDK2 | |
| SCHEMBL7370817 | 0.77 | HTT (0.51) | FLT3ALDH1A1LMNA | |
| SCHEMBL7365352 | 0.76 | KMT2A (0.50) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |