Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366169 | 0.89 | FLT3 (0.43) | FLT3CDK2CSNK2A1DYRK1AJAK2 | |
| SCHEMBL7367473 | 0.88 | SMN1; SMN2 (0.46) | FLT3NTRK1NTRK2NPC1POLB | |
| SCHEMBL7367977 | 0.85 | JAK2 (0.46) | FLT3NTRK1NTRK2NPC1RAB9A | |
| SCHEMBL7369592 | 0.84 | NR1H4 (0.50) | FLT3NTRK1NTRK2KCNK3KCNK9 | |
| SCHEMBL7366495 | 0.82 | FLT3 (0.45) | FLT3NTRK1NTRK2NPC1RAB9A | |
| SCHEMBL7371218 | 0.80 | MEN1 (0.53) | FLT3POLBRAB9ACSNK2A1MAPK1 | |
| SCHEMBL7368426 | 0.79 | NPC1 (0.54) | FLT3NPC1POLBRAB9ACDK2 | |
| SCHEMBL7371977 | 0.79 | NR1H4 (0.46) | FLT3KCNK9TP53SMN1; SMN2 | |
| SCHEMBL7370817 | 0.79 | HTT (0.51) | FLT3POLBRAB9AALDH1A1LMNA | |
| SCHEMBL7365502 | 0.78 | JAK2 (0.41) | FLT3NTRK1NTRK2CDK2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |