Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316396 | 0.75 | MME (0.53) | POLB | |
| Phosphoric Acid SCHEMBL5804027 | 0.75 | CYP3A4 (0.46) | LTA4HSMN1; SMN2TOP2APOLB | |
| SCHEMBL10790828 | 0.74 | MME (0.52) | POLB | |
| SCHEMBL27439930 | 0.71 | PRSS1 (0.71) | SMN1; SMN2TOP2APOLBL3MBTL1 | |
| SCHEMBL512494 | 0.71 | CYP3A4 (0.49) | LTA4HTOP2A | |
| SCHEMBL10258404 | 0.71 | CYP3A4 (0.49) | LTA4HTOP2A | |
| SCHEMBL7708927 | 0.71 | NPC1 (0.48) | SMN1; SMN2POLBL3MBTL1 | |
| Oxalic Acid SCHEMBL10964286 | 0.69 | CYP3A4 (0.47) | LTA4HSMN1; SMN2TOP2A | |
| SCHEMBL8657200 | 0.69 | L3MBTL1 (0.59) | SMN1; SMN2TOP2AL3MBTL1 | |
| SCHEMBL29029672 | 0.69 | SMN1; SMN2 (0.48) | SMN1; SMN2TOP2APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |