Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367028 | 0.83 | FOLH1 (0.55) | CYP1A2 | |
| SCHEMBL7362963 | 0.78 | CYP1A2 (0.47) | GAACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7440491 | 0.78 | FOLH1 (0.51) | CYP1A2 | |
| SCHEMBL7361616 | 0.77 | FOLH1 (0.48) | CYP1A2 | |
| SCHEMBL7365235 | 0.76 | MME (0.54) | TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL7367466 | 0.75 | ANPEP (0.47) | MMP1CYP1A2 | |
| SCHEMBL7361620 | 0.74 | FOLH1 (0.45) | CYP1A2 | |
| SCHEMBL7363389 | 0.74 | FOLH1 (0.49) | CYP1A2 | |
| SCHEMBL7364484 | 0.73 | ANPEP (0.50) | — | |
| SCHEMBL7366262 | 0.72 | LTA4H (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | claimed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | claimed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |