Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CPA3 | P15088 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178867 | 0.87 | LDHA (0.67) | POLBLDHAMMP1MMP2MMP3 | |
| SCHEMBL3965849 | 0.86 | ESR1 (0.58) | POLBKMT2ACPA1CPB1CPA3 | |
| SCHEMBL1914987 | 0.85 | CPA1 (0.66) | MMP2MMP9KMT2ACPA1CPB1 | |
| SCHEMBL901408 | 0.85 | CPA1 (0.66) | MMP2MMP9KMT2ACPA1CPB1 | |
| SCHEMBL2398335 | 0.85 | CPA1 (0.66) | MMP2MMP9KMT2ACPA1CPB1 | |
| SCHEMBL16798224 | 0.84 | MMP2 (0.51) | POLBMMP2MMP9KMT2APPARG | |
| SCHEMBL3664929 | 0.84 | KMT2A (0.59) | POLBALDH1A1KMT2APPARGEPHX2 | |
| SCHEMBL4607790 | 0.84 | CPA1 (0.47) | POLBALDH1A1KMT2ACPA1CPB1 | |
| SCHEMBL28201178 | 0.84 | EPHX2 (0.64) | POLBLDHAKMT2APPARGEPHX2 | |
| SCHEMBL10441763 | 0.83 | LTA4H (0.64) | PPARGFFAR1CPA1CPB1CPA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242600-B1 | ANTIISCHEMIC AGENTS, ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0970071-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998039324-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-11 | — | — | WO | disclosed |
| EP-0217286-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1987-04-08 | — | — | EP | disclosed |