Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372989 | 0.79 | MCL1 (0.39) | MCL1RORCNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7410984 | 0.79 | MCL1 (0.39) | MCL1RORCNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7370318 | 0.77 | KDM4E (0.42) | TAAR1LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7371185 | 0.76 | GRIA1 (0.40) | MCL1RORCNPC1RAB9ANPSR1 | |
| SCHEMBL7049750 | 0.76 | GRIA1 (0.40) | MCL1RORCNPC1RAB9ANPSR1 | |
| SCHEMBL8125475 | 0.76 | RORC (0.35) | MCL1RORCNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7369992 | 0.73 | SMN1; SMN2 (0.42) | TDO2NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8378931 | 0.73 | MEN1 (0.40) | TDO2RORCNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8125784 | 0.72 | RORC (0.40) | TDO2RORCNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8380072 | 0.70 | RAB9A (0.42) | MCL1TDO2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994107-A1 | 5-Arylisoxazol-4-yl-substituted 2-amino carboxylic acid compounds | H. LUNDBECK A/S (DK) | 2000-04-19 | — | — | EP | disclosed |
| EP-0726896-A1 | 5-ARYLISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | H. LUNDBECK A/S (DK) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012587-A1 | 5-ARYLISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | H. LUNDBECK A/S (DK) | 1995-05-11 | — | — | WO | disclosed |