Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GRM6 | O15303 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372989 | 1.00 | MCL1 (0.39) | MCL1RORCMEN1KMT2AALDH1A1 | |
| SCHEMBL7049750 | 0.88 | GRIA1 (0.40) | MCL1RORCNPC1RAB9ANPSR1 | |
| SCHEMBL7371185 | 0.88 | GRIA1 (0.40) | MCL1RORCNPC1RAB9ANPSR1 | |
| SCHEMBL8128585 | 0.81 | KIF11 (0.39) | MEN1KMT2ACYP2C19GRM6ALOX15 | |
| SCHEMBL8128581 | 0.81 | KIF11 (0.39) | MEN1KMT2ACYP2C19GRM6ALOX15 | |
| SCHEMBL7452730 | 0.80 | SLC1A3 (0.35) | MEN1KMT2ACYP2C19GRM6ALOX15 | |
| SCHEMBL7452720 | 0.80 | SLC1A3 (0.35) | MEN1KMT2ACYP2C19GRM6ALOX15 | |
| SCHEMBL7365968 | 0.79 | TAAR1 (0.42) | MCL1RORCMEN1KMT2ANPC1 | |
| SCHEMBL8119688 | 0.77 | GRIA1 (0.53) | MCL1RORCMEN1KMT2ACYP2C19 | |
| SCHEMBL8119682 | 0.77 | GRIA1 (0.53) | MCL1RORCMEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994107-A1 | 5-Arylisoxazol-4-yl-substituted 2-amino carboxylic acid compounds | H. LUNDBECK A/S (DK) | 2000-04-19 | — | — | EP | disclosed |
| EP-0726896-A1 | 5-ARYLISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | H. LUNDBECK A/S (DK) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012587-A1 | 5-ARYLISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | H. LUNDBECK A/S (DK) | 1995-05-11 | — | — | WO | disclosed |