Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30010967 | 0.82 | EDNRA (0.47) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL8378931 | 0.79 | MEN1 (0.40) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL8380072 | 0.79 | RAB9A (0.42) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL7370615 | 0.78 | ERCC1 (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL7367699 | 0.76 | ERCC1 (0.43) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL7371924 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL7365968 | 0.73 | TAAR1 (0.42) | SMN1; SMN2RAB9ANPC1MAPK1KDM4E | |
| SCHEMBL7370168 | 0.73 | KDM4E (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL13960193 | 0.72 | TDO2 (0.44) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL27369371 | 0.72 | RAB9A (0.40) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1056837-C | 5-arylisoxazol-4-yl-substituted 2-aminocarboxylic acid compounds | LUNDBECK & CO AS H (DK) | 2000-09-27 | — | — | CN | disclosed |
| EP-0994107-A1 | 5-Arylisoxazol-4-yl-substituted 2-amino carboxylic acid compounds | H. LUNDBECK A/S (DK) | 2000-04-19 | — | — | EP | disclosed |
| CN-1136810-A | 5-arylisoxazol-4-yl-substituted 2-aminocarboxylic acid compounds | LUNDBECK & CO AS H (DK) | 1996-11-27 | — | — | CN | disclosed |
| EP-0726896-A1 | 5-ARYLISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | H. LUNDBECK A/S (DK) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012587-A1 | 5-ARYLISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | H. LUNDBECK A/S (DK) | 1995-05-11 | — | — | WO | disclosed |