Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17449944 | 0.87 | KDM4E (0.49) | KDM4ELTA4H | |
| SCHEMBL1251880 | 0.87 | KDM4E (0.53) | KDM4EMEN1KMT2ACHRM2DPP7 | |
| SCHEMBL7366849 | 0.85 | EPHX2 (0.56) | KDM4EMEN1KMT2ACHRM2 | |
| SCHEMBL8495474 | 0.85 | LTA4H (0.55) | KDM4EMEN1KMT2ALTA4H | |
| SCHEMBL206952 | 0.83 | MEN1 (0.57) | KDM4EMEN1KMT2ACHRM2DPP7 | |
| SCHEMBL15888177 | 0.80 | PPARG (0.45) | KDM4EMEN1KMT2AATM | |
| SCHEMBL16696334 | 0.79 | FAAH (0.56) | CNR1KMT2ACNR2 | |
| SCHEMBL3182451 | 0.79 | ALDH1A1 (0.43) | CNR1KMT2ALTA4HMIF | |
| SCHEMBL209395 | 0.79 | KMT2A (0.59) | KDM4EMEN1KMT2AATM | |
| SCHEMBL20195735 | 0.78 | KDM4E (0.43) | KDM4ELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |