SCHEMBL736625

SCHEMBL736625

C=CCNC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.58
KDM4E B2RXH2 3/20 0.44
LMNA P02545 2/20 0.44
ALDH1A1 P00352 4/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RECQL P46063 1/20 0.39
TSHR P16473 1/20 0.36
KMT2A Q03164 4/20 0.35
MEN1 O00255 2/20 0.34
MAPT P10636 1/20 0.34
PKM P14618 1/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
RAD52 P43351 1/20 0.34
GFER P55789 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KDM1A O60341 1/20 0.33
SLC2A1 P11166 1/20 0.33
HTT P42858 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11633416 0.78 ALDH1A1 (0.44) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL4995790 0.78 GAA (0.42) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL11652673 0.77 GAA (0.47) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL8434608 0.76 GAA (0.50) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL10079239 0.76 GAA (0.43) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL22368528 0.74 GAA (0.35) GAA
SCHEMBL8433236 0.74 GAA (0.49) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL11290082 0.73 GAA (0.45) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL7072409 0.73 GAA (0.34) GAAPOLB
SCHEMBL7072412 0.73 GAA (0.37) GAAKDM4EKMT2AL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105348525-B A kind of low alkalinity polymerized hindered amine light stabilizer and preparation method thereof 北京天罡助剂有限责任公司 2017-10-27 CN claimed
EP-1554241-B1 S-(ALPHA,ALPHA'-DISUBSTITUTED-ALPHA\"-ACETIC ACID) SUBSTITUTED DITHIOCARBONATE DERIVATIVES FOR CONTROLLED RADICAL POLYMERISATIONS, PROCESS AND POLYMERS MADE THEREFROM LUBRIZOL ADVANCED MAT INC (US) 2015-03-18 EP claimed
US-8709543-B2 Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom LUBRIZOL ADVANCED MATERIALS, INC. (US) 2014-04-29 US claimed
EP-1773905-B1 HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS, POLYMERS, AND COPOLYMERS, AND POLYURETHANES AND URETHANE ACRYLICS MADE THEREFROM LUBRIZOL ADVANCED MAT INC (US) 2013-10-09 EP claimed
US-8492576-B2 Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-07-23 US claimed
US-20120171914-A1 Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-07-05 US claimed
US-7851582-B2 S-(α, α′-disubstituted-α″-acetic acid)—substituted dithiocarbonate derivatives for controlled radical polymerizations, process and polymers made therefrom LUBRIZOL ADVANCED MATERIALS, INC. (US) 2010-12-14 US claimed
US-20090312496-A1 Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom LAI JOHN TA-YUAN 2009-12-17 US claimed
US-7557235-B2 Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom LUBRIZOL ADVANCED MATERIALS, INC. (US) 2009-07-07 US claimed
US-20080050995-A1 Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom LUBRIZOL ADVANCED MATERIALS, INC. 2008-02-28 US claimed
EP-1786848-A1 POLYURETHANES AND URETHANE ACRYLICS MADE FROM HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS Noveon, Inc. (US) 2007-05-23 EP claimed
EP-1773905-A1 HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS, POLYMERS, AND COPOLYMERS, AND POLYURETHANES AND URETHANE ACRYLICS MADE THEREFROM Noveon, Inc. (US) 2007-04-18 EP claimed
WO-2006020116-A1 HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS, POLYMERS, AND COPOLYMERS, AND POLYURETHANES AND URETHANE ACRYLICS MADE THEREFROM NOVEON, INC. (US) 2006-02-23 WO claimed
WO-2006020281-A1 POLYURETHANES AND URETHANE ACRYLICS MADE FROM HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS NOVEON, INC. (US) 2006-02-23 WO claimed
US-20050009999-A1 Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom LUBRIZOL ADVANCED MATERIALS, INC. 2005-01-13 US claimed
EP-0665258-B1 Piperidenyle compounds and their use as a photostabilizer for polymers RHODIA CHIMIE SA (FR) 1998-07-01 EP claimed
EP-0388321-B1 Piperidinyle compounds and their use as a photostabilizer for polymers RHONE POULENC CHIMIE (FR) 1996-12-18 EP claimed
EP-3699182-B1 ORGANIC SILICON COMPOUND, METHOD FOR PRODUCING THE SAME, AND CURABLE COMPOSITION SHINETSU CHEMICAL CO (JP) 2023-12-13 EP disclosed
US-4223147-A POLYMER STABILIZERS BAYER AKTIENGESELLSCHAFT (DE) 1980-09-16 US disclosed
US-4153596-A PHOTOSTABILITY BAYER AKTIENGESELLSCHAFT (DE) 1979-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120171914-A1 Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom ALKBH3, HAAO, BHMT2 GAA 3244/4885KDM4E 1723/4885LMNA 4005/4885
US-20090312496-A1 Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom ALKBH3, BHMT2, ALKBH2 GAA 3918/4885KDM4E 1609/4885LMNA 4238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.