Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 13/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9913603 | 0.81 | TSHR (0.56) | TDP1TSHRCYP3A4 | |
| SCHEMBL5089045 | 0.76 | VCAM1 (0.51) | VCAM1MAPK1CYP3A4 | |
| SCHEMBL9109948 | 0.75 | TSHR (0.53) | TDP1TSHRCYP3A4 | |
| SCHEMBL26218863 | 0.74 | ALDH1A1 (0.53) | VCAM1TDP1TSHRMAPK1CYP3A4 | |
| SCHEMBL656412 | 0.74 | DRD2 (0.51) | VCAM1NPBWR1MCHR1CYP3A4 | |
| SCHEMBL14625431 | 0.74 | SLC6A4 (0.50) | — | |
| SCHEMBL26218864 | 0.73 | ALDH1A1 (0.51) | VCAM1TDP1TSHRCYP3A4 | |
| SCHEMBL6400223 | 0.73 | VCAM1 (0.41) | VCAM1MAPK1NPBWR1MCHR1 | |
| SCHEMBL7424106 | 0.73 | VCAM1 (0.48) | VCAM1MAPK1NPBWR1MCHR1CYP3A4 | |
| SCHEMBL7102532 | 0.73 | LMNA (0.47) | VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206446-A1 | CARBOXYLIC ACID AMIDES, THEIR PRODUCTION AND THEIR USE AS DRUGS | Boehringer Ingelheim Pharma KG (DE) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001010823-A1 | CARBOXYLIC ACID AMIDES, THEIR PRODUCTION AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-02-15 | — | — | WO | disclosed |