Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTPS1 | Q14703 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.38 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.38 |
| ▸ | RPS17 | P08708 | 1/20 | 0.38 |
| ▸ | RPSA | P08865 | 1/20 | 0.38 |
| ▸ | RPS2 | P15880 | 1/20 | 0.38 |
| ▸ | RPL35A | P18077 | 1/20 | 0.38 |
| ▸ | RPL7 | P18124 | 1/20 | 0.38 |
| ▸ | RPL17 | P18621 | 1/20 | 0.38 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.38 |
| ▸ | RPS3 | P23396 | 1/20 | 0.38 |
| ▸ | RPS12 | P25398 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366435 | 0.73 | MBTPS1 (0.47) | MBTPS1HTR2CHTR2BKCNH2ALOX5 | |
| SCHEMBL7372177 | 0.72 | LTA4H (0.46) | LTA4HPARP10ALOX5FFAR1FFAR4 | |
| SCHEMBL7370862 | 0.72 | MBTPS1 (0.48) | MBTPS1CACNA1BKCNH2 | |
| SCHEMBL8637317 | 0.69 | MBTPS1 (0.49) | MBTPS1LTA4HKCNH2 | |
| SCHEMBL16527961 | 0.69 | PYGL (0.46) | MBTPS1KCNH2RPS6KB1 | |
| SCHEMBL7041151 | 0.69 | CACNA1B (0.77) | MBTPS1HTR2CHTR2BCACNA1BNPC1 | |
| SCHEMBL27936854 | 0.68 | CTSD (0.50) | KCNH2RPS6KB1 | |
| SCHEMBL27936852 | 0.68 | CTSD (0.50) | KCNH2RPS6KB1 | |
| SCHEMBL5143426 | 0.68 | CTSD (0.55) | KCNH2 | |
| SCHEMBL1623585 | 0.68 | CTSD (0.55) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | claimed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |