Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTPS1 | Q14703 | 3/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370864 | 0.84 | MBTPS1 (0.52) | MBTPS1SLC6A2SLC6A4ALOX5SLC6A3 | |
| SCHEMBL7368517 | 0.78 | CACNA1B (0.47) | MBTPS1SLC6A2SLC6A4ALOX5SLC6A3 | |
| SCHEMBL7373750 | 0.77 | ALOX5 (0.45) | TRPM8ALOX5KCNH2HTR2CHTR2B | |
| SCHEMBL7366434 | 0.73 | MBTPS1 (0.47) | MBTPS1ALOX5KCNH2HTR2CHTR2B | |
| SCHEMBL7372181 | 0.73 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL16527961 | 0.69 | PYGL (0.46) | MBTPS1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL966683 | 0.68 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL27936852 | 0.68 | CTSD (0.50) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL27936854 | 0.68 | CTSD (0.50) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL7366752 | 0.68 | CYP19A1 (0.45) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | claimed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |