Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27455721 | 0.86 | ALDH1A1 (0.57) | KMT2AHDAC1ALDH1A1MAPTHDAC6 | |
| SCHEMBL1852409 | 0.84 | HDAC1 (0.49) | KMT2AHDAC1ALDH1A1MAPTHDAC6 | |
| SCHEMBL14220086 | 0.84 | KMT2A (0.49) | KMT2AHDAC1ALDH1A1MAPTHDAC6 | |
| SCHEMBL8281923 | 0.84 | KMT2A (0.49) | KMT2AHDAC1ALDH1A1MAPTHDAC6 | |
| SCHEMBL6821062 | 0.82 | ALDH1A1 (0.58) | KMT2AALDH1A1POLBTSHR | |
| SCHEMBL19190038 | 0.82 | ALDH1A1 (0.58) | KMT2AALDH1A1POLBTSHRGAA | |
| SCHEMBL12133623 | 0.80 | KMT2A (0.76) | KMT2AHDAC1ALDH1A1MAPTHDAC6 | |
| SCHEMBL18779301 | 0.79 | HDAC1 (0.57) | KMT2AHDAC1KIF11PDK2HDAC3 | |
| SCHEMBL7370748 | 0.79 | LMNA (0.49) | KMT2AHDAC1ALDH1A1MAPTKDM4E | |
| SCHEMBL1800569 | 0.79 | KMT2A (0.63) | KMT2AHDAC1ALDH1A1MAPTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |