Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 5/20 | 0.41 |
| ▸ | MMP13 | P45452 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361327 | 0.88 | MMP1 (0.43) | MMP1MMP13MMP2MMP9 | |
| SCHEMBL6382556 | 0.79 | HTT (0.43) | HTTNPSR1MMP1MMP13KMT2A | |
| SCHEMBL6378307 | 0.71 | HTT (0.59) | HTTNPSR1MMP1MMP13KMT2A | |
| Hydrochloric Acid SCHEMBL7207769 | 0.70 | HTT (0.55) | HTTNPSR1MMP1MMP13KMT2A | |
| SCHEMBL8521710 | 0.70 | HTT (0.58) | HTTNPSR1MMP1MMP13KMT2A | |
| SCHEMBL6378086 | 0.70 | BMP1 (0.45) | MMP1MMP13MMP2MMP9 | |
| SCHEMBL7075250 | 0.69 | MMP13 (0.59) | HTTNPSR1MMP1MMP13KMT2A | |
| SCHEMBL6626569 | 0.69 | HTT (0.56) | HTTNPSR1MMP1MMP13KMT2A | |
| SCHEMBL6382945 | 0.67 | BMP1 (0.45) | MMP1MMP13KMT2AMEN1MMP2 | |
| SCHEMBL7077694 | 0.66 | MMP13 (0.63) | HTTNPSR1MMP1MMP13KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929519-A1 | $g(b)-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013340-A1 | β-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-02 | — | — | WO | disclosed |