Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 12/20 | 0.42 |
| ▸ | MMP2 | P08253 | 4/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 7/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366561 | 0.88 | HTT (0.42) | MMP1MMP13MMP2MMP9 | |
| SCHEMBL6378086 | 0.80 | BMP1 (0.45) | MMP1BMP1MMP13MMP2ADAM17 | |
| SCHEMBL6382945 | 0.77 | BMP1 (0.45) | MMP1BMP1MMP13MMP2ADAM17 | |
| SCHEMBL6377102 | 0.75 | MMP2 (0.44) | MMP1BMP1MMP13MMP2ADAM17 | |
| SCHEMBL6378620 | 0.73 | MMP1 (0.58) | MMP1MMP13MMP2ADAM17MMP9 | |
| Hydrochloric Acid SCHEMBL7862116 | 0.72 | MMP13 (0.59) | MMP1MMP13MMP2ADAM17MMP9 | |
| SCHEMBL8441721 | 0.72 | MMP1 (0.57) | MMP1MMP13MMP2ADAM17MMP9 | |
| SCHEMBL6764587 | 0.72 | MMP1 (0.57) | MMP1MMP13MMP2ADAM17MMP9 | |
| SCHEMBL7361398 | 0.70 | NPC1 (0.37) | MMP1MMP13MMP2MMP9CA1 | |
| SCHEMBL6382556 | 0.70 | HTT (0.43) | MMP1BMP1MMP13MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929519-A1 | $g(b)-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-21 | — | — | EP | claimed |
| WO-1998013340-A1 | β-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-02 | — | — | WO | claimed |
| EP-0929519-A1 | $g(b)-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013340-A1 | β-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-02 | — | — | WO | disclosed |