Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGFR | P43088 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401586 | 0.87 | SLC7A5 (0.38) | GRM2GRM3 | |
| SCHEMBL7361669 | 0.86 | SMN1; SMN2 (0.42) | GRM2GRM3SMN1; SMN2PTGFRFFAR1 | |
| SCHEMBL7364664 | 0.86 | RARB (0.38) | GRM2GRM3 | |
| SCHEMBL7396689 | 0.86 | KMT2A (0.37) | GRM2GRM3FFAR4FFAR1 | |
| SCHEMBL7399248 | 0.86 | HSD17B10 (0.45) | GRM2GRM3FFAR4 | |
| SCHEMBL7367779 | 0.84 | CPA1 (0.37) | GRM2GRM3CPA1FFAR4HTT | |
| SCHEMBL7363860 | 0.83 | PTGER1 (0.42) | GRM2GRM3TAAR1PTGER1PTGFR | |
| SCHEMBL7360786 | 0.82 | LDHA (0.47) | SMN1; SMN2PTGFRFFAR1 | |
| SCHEMBL7360104 | 0.79 | CYP1A2 (0.46) | — | |
| SCHEMBL7363028 | 0.78 | SLC6A2 (0.41) | GRM2TAAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771196-A4 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0771196-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996007405-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |