Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PTGFR | P43088 | 1/20 | 0.43 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362960 | 0.85 | GRM2 (0.55) | ALDH1A1KMT2APTGFRMEN1SMN1; SMN2 | |
| SCHEMBL7361669 | 0.85 | SMN1; SMN2 (0.42) | ALDH1A1KMT2APTGFRKDM4EMEN1 | |
| SCHEMBL7399248 | 0.82 | HSD17B10 (0.45) | ALDH1A1KMT2AKDM4EMEN1CYP2C19 | |
| SCHEMBL7364664 | 0.82 | RARB (0.38) | ALDH1A1KMT2AKDM4EMEN1CYP2C19 | |
| SCHEMBL7366774 | 0.82 | GRM2 (0.48) | PTGFRFFAR1SMN1; SMN2 | |
| SCHEMBL7396689 | 0.82 | KMT2A (0.37) | ALDH1A1KMT2AKDM4EMEN1CYP2C19 | |
| SCHEMBL7362412 | 0.82 | HSD17B10 (0.48) | ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL7368285 | 0.80 | PTGFR (0.45) | KMT2APTGFRMEN1SMN1; SMN2 | |
| SCHEMBL7360104 | 0.78 | CYP1A2 (0.46) | — | |
| SCHEMBL7369261 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771196-A4 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0771196-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996007405-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |