Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489584 | 0.86 | HTT (0.49) | HTTKDM4EMAPTTDP1LMNA | |
| SCHEMBL6193853 | 0.78 | HTT (0.54) | HTTKDM4EMAPTTDP1LMNA | |
| SCHEMBL8489480 | 0.74 | LMNA (0.47) | KDM4EMAPTTDP1LMNASMN1; SMN2 | |
| SCHEMBL31365743 | 0.72 | HTT (0.54) | HTTKDM4EMAPTTDP1LMNA | |
| SCHEMBL20668933 | 0.71 | S100A4 (0.42) | HTTKDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL7596891 | 0.71 | ALDH1A1 (0.44) | HTTKDM4EMAPTTDP1LMNA | |
| SCHEMBL29350633 | 0.70 | MAPK1 (0.62) | HTTKDM4EMAPTTDP1LMNA | |
| SCHEMBL1683978 | 0.70 | KDM4E (0.53) | HTTKDM4EMAPTTDP1LMNA | |
| SCHEMBL9488962 | 0.69 | HTT (0.54) | HTTKDM4EMAPTTDP1LMNA | |
| SCHEMBL5212814 | 0.69 | MAPK1 (0.71) | HTTKDM4EMAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046230-A1 | FLUORESCENT ORGANIC COMPOUNDS | DIATECH PTY. LTD. (AU) | 1999-09-16 | — | — | WO | claimed |