Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.34 |
| ▸ | ITGAV | P06756 | 9/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176077 | 0.84 | ITGAV (0.46) | ITGB3ITGA2BITGAV | |
| SCHEMBL7367243 | 0.82 | SLC1A3 (0.47) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL7369516 | 0.77 | ITGB3 (0.48) | ITGB3ITGA2BITGAV | |
| SCHEMBL7367606 | 0.76 | SLC1A3 (0.36) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7373306 | 0.75 | GLS (0.39) | ITGB3ITGA2BITGAV | |
| SCHEMBL7366550 | 0.74 | SLC1A2 (0.41) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8168330 | 0.67 | ITGAV (0.44) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8222330 | 0.65 | ITGB3 (0.36) | ITGB3ITGA2BITGAV | |
| SCHEMBL8176082 | 0.64 | ITGAV (0.65) | ITGB3ITGA2BITGAV | |
| SCHEMBL8168501 | 0.63 | ITGB3 (0.42) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049693-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS $g(a) v?$g(b) 3? ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2000-11-08 | — | — | EP | claimed |
| WO-1999026945-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS αvβ3 ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-06-03 | — | — | WO | claimed |
| EP-1049693-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS $g(a) v?$g(b) 3? ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999026945-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS αvβ3 ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |