Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.42 |
| ▸ | ITGAV | P06756 | 6/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177319 | 0.92 | ITGB3 (0.36) | ITGB3ITGAVITGA2B | |
| Hydrochloric Acid SCHEMBL8222330 | 0.91 | ITGB3 (0.36) | ITGB3ITGAVITGA2B | |
| SCHEMBL8216110 | 0.85 | F2 (0.33) | ITGB3ITGA2B | |
| SCHEMBL7366550 | 0.82 | SLC1A2 (0.41) | — | |
| SCHEMBL8168513 | 0.79 | ITGB3 (0.53) | ITGB3ITGAVITGA2B | |
| SCHEMBL8168330 | 0.76 | ITGAV (0.44) | ITGB3ITGAVITGA2B | |
| SCHEMBL7367606 | 0.75 | SLC1A3 (0.36) | — | |
| Hydrochloric Acid SCHEMBL8215964 | 0.75 | GLS (0.33) | — | |
| SCHEMBL8176077 | 0.73 | ITGAV (0.46) | ITGB3ITGAVITGA2B | |
| SCHEMBL8218077 | 0.73 | GLS (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153628-A | 1,3,4-thiadiazoles and 1,3,4-Oxadiazoles as αv β3 antagonists | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-28 | — | — | US | disclosed |