Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 9/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 9/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 8/20 | 0.36 |
| ▸ | GLS | O94925 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366550 | 0.92 | SLC1A2 (0.41) | SLC1A3SLC1A2SLC1A1GLS | |
| SCHEMBL8177319 | 0.84 | ITGB3 (0.36) | GLSF2FBP1 | |
| Hydrochloric Acid SCHEMBL8222330 | 0.84 | ITGB3 (0.36) | GLSF2FBP1 | |
| SCHEMBL8216110 | 0.80 | F2 (0.33) | GLSF2FBP1 | |
| SCHEMBL7366853 | 0.76 | SLC1A3 (0.34) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8168501 | 0.75 | ITGB3 (0.42) | — | |
| Hydrochloric Acid SCHEMBL8215964 | 0.75 | GLS (0.33) | GLS | |
| SCHEMBL8218077 | 0.75 | GLS (0.33) | GLS | |
| SCHEMBL7367243 | 0.73 | SLC1A3 (0.47) | SLC1A3SLC1A2SLC1A1F2ALDH1A1 | |
| SCHEMBL8176077 | 0.65 | ITGAV (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049693-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS $g(a) v?$g(b) 3? ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2000-11-08 | — | — | EP | claimed |
| WO-1999026945-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS αvβ3 ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-06-03 | — | — | WO | claimed |
| EP-1049693-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS $g(a) v?$g(b) 3? ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999026945-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS αvβ3 ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |