Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373402 | 0.89 | S100A4 (0.32) | S100A4MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7376611 | 0.85 | ALDH1A1 (0.38) | S100A4FGFR1ALDH1A1CDK8 | |
| SCHEMBL7372821 | 0.85 | S100A4 (0.36) | S100A4MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL7299347 | 0.84 | MEN1 (0.37) | S100A4FGFR1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7298334 | 0.84 | TNKS (0.33) | MAPTLMNA | |
| SCHEMBL7301120 | 0.82 | NR4A2 (0.31) | MAPTLMNA | |
| SCHEMBL7377531 | 0.81 | POLB (0.38) | S100A4MAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7374768 | 0.81 | CHUK (0.37) | CDK8 | |
| SCHEMBL7370169 | 0.81 | CHUK (0.37) | FGFR1KDM4EHSD17B10CDK8 | |
| SCHEMBL7300227 | 0.79 | MEN1 (0.37) | S100A4MAPTKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308792-B1 | AZACHROMANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-4931454-A | Azachroman derivatives with effects on the cardiovascular system | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-06-05 | — | — | US | disclosed |