Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30808595 | 0.91 | MAPT (0.65) | HDAC1HDAC6MAPTTP53ALDH1A1 | |
| SCHEMBL10588893 | 0.87 | HDAC1 (0.55) | HDAC1HDAC6MAPTTP53ALDH1A1 | |
| SCHEMBL10588991 | 0.84 | ALDH1A1 (0.66) | HDAC1HDAC6MAPTTP53ALDH1A1 | |
| SCHEMBL5940974 | 0.81 | MAPT (0.47) | HDAC1HDAC6MAPTTP53ALDH1A1 | |
| SCHEMBL13444609 | 0.80 | ALDH1A1 (0.54) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| Bromide SCHEMBL27458290 | 0.80 | MAPT (0.46) | HDAC1HDAC6MAPTTP53ALDH1A1 | |
| Bromide SCHEMBL2951034 | 0.80 | MAPT (0.46) | HDAC1HDAC6MAPTTP53ALDH1A1 | |
| SCHEMBL8853801 | 0.78 | HDAC1 (0.51) | HDAC1HDAC6MAPTTP53ALDH1A1 | |
| SCHEMBL9802833 | 0.77 | MAPT (0.53) | HDAC1HDAC6MAPTTP53ALDH1A1 | |
| SCHEMBL3965007 | 0.74 | MAPT (0.52) | HDAC1HDAC6MAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292923-A2 | Piperidine compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-11-30 | — | — | EP | claimed |
| EP-0125056-A2 | Condensed, seven-membered ring compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-11-14 | — | — | EP | disclosed |