Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588991 | 0.83 | ALDH1A1 (0.66) | MAPTALDH1A1LMNAMAPK1GFER | |
| SCHEMBL7366935 | 0.77 | HDAC1 (0.56) | MAPTALDH1A1LMNAMAPK1GFER | |
| SCHEMBL10588893 | 0.76 | HDAC1 (0.55) | MAPTALDH1A1LMNAMAPK1GFER | |
| SCHEMBL30808595 | 0.69 | MAPT (0.65) | MAPTALDH1A1LMNAMAPK1GFER | |
| SCHEMBL8853801 | 0.68 | HDAC1 (0.51) | MAPTALDH1A1LMNAMAPK1GFER | |
| SCHEMBL23950277 | 0.66 | HDAC1 (1.00) | HDAC1HDAC6 | |
| SCHEMBL22275060 | 0.66 | HDAC1 (0.66) | MAPTALDH1A1MAPK1GFERHDAC1 | |
| SCHEMBL3965007 | 0.65 | MAPT (0.52) | MAPTALDH1A1LMNAMAPK1GFER | |
| SCHEMBL30808624 | 0.64 | MAPT (0.51) | MAPTALDH1A1LMNAMAPK1GFER | |
| SCHEMBL9629708 | 0.64 | HDAC1 (0.47) | MAPTALDH1A1LMNAMAPK1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055464-A | Cognition activators, diuretics, antiulcer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1991-10-08 | — | — | US | claimed |