Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGFR | P43088 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363860 | 0.84 | PTGER1 (0.42) | PTGER1PTGFRALDH1A1TAAR1CYP1A2 | |
| SCHEMBL7368285 | 0.83 | PTGFR (0.45) | PTGFRTAAR1MEN1KMT2A | |
| SCHEMBL7368270 | 0.82 | GRM2 (0.52) | ALDH1A1TDP1S1PR5CYP1A2KMT2A | |
| SCHEMBL7361669 | 0.81 | SMN1; SMN2 (0.42) | PTGFRALDH1A1TDP1S1PR1S1PR5 | |
| SCHEMBL7365439 | 0.80 | HRH1 (0.43) | ALDH1A1FFAR1PPARA | |
| SCHEMBL7400111 | 0.79 | GRM2 (0.52) | ALDH1A1POLBTAAR1CYP1A2FFAR1 | |
| SCHEMBL7366774 | 0.78 | GRM2 (0.48) | PTGER1PTGFRTAAR1FFAR1 | |
| SCHEMBL7360104 | 0.76 | CYP1A2 (0.46) | CYP1A2 | |
| SCHEMBL7401586 | 0.76 | SLC7A5 (0.38) | ALDH1A1POLBCYP1A2MEN1KMT2A | |
| SCHEMBL7361069 | 0.76 | CYP1A2 (0.45) | ALDH1A1TAAR1CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771196-A4 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0771196-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996007405-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |