Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369261 | 0.89 | ALDH1A1 (0.41) | MEN1KMT2A | |
| SCHEMBL7365439 | 0.86 | HRH1 (0.43) | — | |
| SCHEMBL7362412 | 0.84 | HSD17B10 (0.48) | MTNR1AMTNR1BTAAR1MEN1KMT2A | |
| SCHEMBL7367030 | 0.83 | PTGER1 (0.42) | PTGFRTAAR1MEN1KMT2A | |
| SCHEMBL7363860 | 0.81 | PTGER1 (0.42) | PTGFRTAAR1KDM1AMAOAMAOB | |
| SCHEMBL7363028 | 0.81 | SLC6A2 (0.41) | SMN1; SMN2TAAR1MEN1KMT2AKDM1A | |
| SCHEMBL7360786 | 0.80 | LDHA (0.47) | PTGFRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7368270 | 0.79 | GRM2 (0.52) | MTNR1ASMN1; SMN2KMT2A | |
| SCHEMBL7362960 | 0.78 | GRM2 (0.55) | PTGFRMTNR1AMTNR1BSMN1; SMN2TAAR1 | |
| SCHEMBL7366774 | 0.78 | GRM2 (0.48) | PTGFRSMN1; SMN2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771196-A4 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0771196-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996007405-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |