Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.36 |
| ▸ | ITGAV | P06756 | 9/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367251 | 1.00 | F2 (0.40) | F2ITGB3ITGAVITGA2BSMN1; SMN2 | |
| SCHEMBL7374464 | 0.84 | ITGB3 (0.41) | ITGB3ITGAVITGA2BNPY5RAGTR1 | |
| SCHEMBL7374471 | 0.84 | ITGB3 (0.41) | ITGB3ITGAVITGA2BNPY5RAGTR1 | |
| SCHEMBL7366867 | 0.81 | ITGB3 (0.42) | F2ITGB3ITGAVITGA2BCXCR4 | |
| SCHEMBL7366861 | 0.81 | ITGB3 (0.42) | F2ITGB3ITGAVITGA2BCXCR4 | |
| SCHEMBL8168332 | 0.79 | ITGB3 (0.56) | F2ITGB3ITGAVITGA2B | |
| SCHEMBL7377522 | 0.73 | ITGB3 (0.36) | F2ITGB3ITGAVITGA2BCXCR4 | |
| SCHEMBL7377515 | 0.73 | ITGB3 (0.36) | F2ITGB3ITGAVITGA2BCXCR4 | |
| SCHEMBL8218081 | 0.69 | GLS (0.34) | F2ITGB3ITGAVITGA2BCXCR4 | |
| SCHEMBL7374249 | 0.69 | ITGB3 (0.43) | ITGB3ITGAVITGA2BSMN1; SMN2CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049693-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS $g(a) v?$g(b) 3? ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999026945-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS αvβ3 ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |