Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.41 |
| ▸ | ITGAV | P06756 | 10/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374471 | 1.00 | ITGB3 (0.41) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL7367251 | 0.84 | F2 (0.40) | ITGB3ITGAVITGA2BNPY5RAGTR1 | |
| SCHEMBL7367256 | 0.84 | F2 (0.40) | ITGB3ITGAVITGA2BNPY5RAGTR1 | |
| SCHEMBL7369525 | 0.83 | ITGB3 (0.41) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL7369530 | 0.83 | ITGB3 (0.41) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL7374456 | 0.82 | SLC1A3 (0.51) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL8179651 | 0.78 | ITGAV (0.63) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL8179647 | 0.78 | ITGAV (0.63) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL7369516 | 0.68 | ITGB3 (0.48) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL7368318 | 0.67 | GLS (0.42) | ITGB3ITGAVITGB1ITGA5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049693-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS $g(a) v?$g(b) 3? ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2000-11-08 | — | — | EP | claimed |
| WO-1999026945-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS αvβ3 ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-06-03 | — | — | WO | claimed |
| EP-1049693-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS $g(a) v?$g(b) 3? ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999026945-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS αvβ3 ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |