Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18554126 | 0.95 | FDPS (0.63) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL17821696 | 0.95 | FDPS (0.58) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL3934768 | 0.89 | FDPS (0.70) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL18574520 | 0.88 | FDPS (0.60) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL3788224 | 0.85 | ALDH1A1 (0.76) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL2559267 | 0.85 | FDPS (0.72) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL27118587 | 0.85 | FDPS (0.72) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL2654920 | 0.84 | FDPS (0.44) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL8886451 | 0.84 | ALDH1A1 (0.50) | FDPSALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9442186 | 0.83 | FDPS (0.90) | FDPSALDH1A1CYP2C9NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | THE UNIVERSITY OF CHICAGO | 2023-05-04 | — | — | US | disclosed |
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | THE UNIVERSITY OF CHICAGO | 2023-05-04 | — | — | US | disclosed |
| EP-3386985-A1 | PBD ANTIBACTERIAL AGENTS | Kings College London (GB) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017098257-A1 | PBD ANTIBACTERIAL AGENTS | KING'S COLLEGE LONDON (GB) | 2017-06-15 | — | — | WO | disclosed |
| US-20150104427-A1 | ENZYME-ASSISTED SPATIAL DECORATION OF BIOMATERIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-04-16 | — | — | US | disclosed |
| EP-0538384-A4 | OXAMIDES | SMITHKLINE BEECHAM CORP (US) | 1995-04-12 | — | — | EP | disclosed |
| US-5393788-A | Phenylalkyl oxamides | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0538384-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000968-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | PPIA, S100A4, S100A6 | FDPS 2079/4885ALDH1A1 2889/4885CYP2C9 3446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.