Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 4/20 | 0.55 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367306 | 0.95 | FDPS (0.67) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL18574520 | 0.93 | FDPS (0.60) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL17821696 | 0.90 | FDPS (0.58) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL8719147 | 0.85 | FDPS (0.87) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL9442183 | 0.85 | FDPS (0.87) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL20211721 | 0.85 | MAPT (0.49) | FDPSALDH1A1CYP2C9NPC1RAB9A | |
| SCHEMBL1101012 | 0.85 | ALDH1A1 (0.45) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL4302353 | 0.85 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP2C19ACHEBCHE | |
| SCHEMBL3934768 | 0.84 | FDPS (0.70) | FDPSALDH1A1CYP2C9NPSR1NPC1 | |
| SCHEMBL9442186 | 0.84 | FDPS (0.90) | FDPSALDH1A1CYP2C9NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12583857-B2 | Anti-liferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | PHEON THERAPEUTICS LTD (GB) | 2026-03-24 | — | — | US | disclosed |
| US-20250011317-A1 | ANTI-PROLIFERATIVE AGENTS | PHEON THERAPEUTICS LTD (GB) | 2025-01-09 | — | — | US | disclosed |
| US-11912700-B2 | Anti-proliferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | PHEON THERAPEUTICS LTD (GB) | 2024-02-27 | — | — | US | disclosed |
| US-11912700-B2 | Anti-proliferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | PHEON THERAPEUTICS LTD (GB) | 2024-02-27 | — | — | US | disclosed |
| US-11912700-B2 | Anti-proliferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | PHEON THERAPEUTICS LTD (GB) | 2024-02-27 | — | — | US | disclosed |
| US-20240002379-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | PHEON THERAPEUTICS LTD (GB) | 2024-01-04 | — | — | US | disclosed |
| EP-4086251-A1 | PIPERIDINOBENZODIAZEPINE COMPOUNDS WITH ANTI PROLIFERATIVE ACTIVITY | Femtogenix Limited (GB) | 2022-11-09 | — | — | EP | disclosed |
| CN-114907345-A | Piperidine-benzodiazepine compound having anti-proliferative activity | 福姆通格尼克斯有限公司 | 2022-08-16 | — | — | CN | disclosed |
| EP-3337795-B1 | PIPERIDINOBENZODIAZEPINE COMPOUNDS WITH ANTI PROLIFERATIVE ACTIVITY | FEMTOGENIX LTD (GB) | 2022-06-22 | — | — | EP | disclosed |
| EP-3337795-B1 | PIPERIDINOBENZODIAZEPINE COMPOUNDS WITH ANTI PROLIFERATIVE ACTIVITY | FEMTOGENIX LTD (GB) | 2022-06-22 | — | — | EP | disclosed |
| US-20190144443-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | PHEON THERAPEUTICS LTD (GB) | 2019-05-16 | — | — | US | disclosed |
| US-20190144443-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | PHEON THERAPEUTICS LTD (GB) | 2019-05-16 | — | — | US | disclosed |
| EP-3455225-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | Femtogenix Limited (GB) | 2019-03-20 | — | — | EP | disclosed |
| US-20180339985-A1 | PDD COMPOUNDS | FEMTOGENIX LIMITED (GB) | 2018-11-29 | — | — | US | disclosed |
| US-20180291021-A1 | PDD COMPOUNDS | PHEON THERAPEUTICS LTD (GB) | 2018-10-11 | — | — | US | disclosed |
| EP-3337795-A1 | PIPERIDINOBENZODIAZEPINE COMPOUNDS WITH ANTI PROLIFERATIVE ACTIVITY | Femtogenix Limited (GB) | 2018-06-27 | — | — | EP | disclosed |
| WO-2017194960-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | FEMTOGENIX LIMITED (GB) | 2017-11-16 | — | — | WO | disclosed |
| WO-2017194960-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | FEMTOGENIX LIMITED (GB) | 2017-11-16 | — | — | WO | disclosed |
| WO-2017032983-A1 | PIPERIDINOBENZODIAZEPINE COMPOUNDS WITH ANTI PROLIFERATIVE ACTIVITY | FEMTOGENIX LIMITED (GB) | 2017-03-02 | — | — | WO | disclosed |
| WO-2017032983-A1 | PIPERIDINOBENZODIAZEPINE COMPOUNDS WITH ANTI PROLIFERATIVE ACTIVITY | FEMTOGENIX LIMITED (GB) | 2017-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12583857-B2 | Anti-liferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | CNR1, MTNR1B, MTNR1A | FDPS 4503/4885ALDH1A1 1463/4885CYP2C9 2075/4885 |
| US-20250011317-A1 | ANTI-PROLIFERATIVE AGENTS | CCND2, BRD2, CCND3 | FDPS 776/4885ALDH1A1 3182/4885CYP2C9 2222/4885 |
| US-20240002379-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | TUBA1C, MTX2, CCNO | FDPS 4838/4885ALDH1A1 2285/4885CYP2C9 941/4885 |
| US-20180291021-A1 | PDD COMPOUNDS | DRD1, DRD3, DRD2 | FDPS 4443/4885ALDH1A1 3010/4885CYP2C9 515/4885 |
| US-20190144443-A1 | ASYMMETRIC CONJUGATE COMPOUNDS | TUBA1C, MTX2, CCNO | FDPS 4843/4885ALDH1A1 2302/4885CYP2C9 945/4885 |
| US-11912700-B2 | Anti-proliferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | MKI67, CCND2, CCND1 | FDPS 1659/4885ALDH1A1 443/4885CYP2C9 3126/4885 |
| US-20180339985-A1 | PDD COMPOUNDS | DRD1, DRD3, DRD2 | FDPS 4381/4885ALDH1A1 2727/4885CYP2C9 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.