Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | FABP6 | P51161 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4398715 | 0.69 | KDM4E (0.48) | CYP1A2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL3082762 | 0.68 | NPC1 (0.42) | CHRM1MDM2CYP1A2CYP2D6CYP19A1 | |
| SCHEMBL27396444 | 0.68 | — | — | |
| SCHEMBL28596689 | 0.65 | NISCH (0.46) | CYP1A2NPC1RAB9AALDH1A1 | |
| SCHEMBL2750495 | 0.65 | HSP90AA1 (0.34) | FABP6 | |
| SCHEMBL6508296 | 0.65 | PDE3B (0.31) | FABP6 | |
| SCHEMBL27856941 | 0.64 | CHRM1 (0.33) | CHRM1MDM2ALDH1A1GAA | |
| SCHEMBL4472253 | 0.63 | — | — | |
| SCHEMBL28934089 | 0.63 | — | — | |
| SCHEMBL7229227 | 0.63 | HPGDS (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459258-A | Preparation and use of 1,2, 4-triazolo [1,5a ] pyridine derivatives | CEPHALON INC | 2012-05-16 | — | — | CN | disclosed |
| WO-1990005531-A1 | METHOD FOR TREATING VASCULAR DISEASES | ABBOTT LABORATORIES (US) | 1990-05-31 | — | — | WO | disclosed |