Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | RAC1 | P63000 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371218 | 0.90 | MEN1 (0.53) | SMN1; SMN2RAB9AFLT3KMT2AMEN1 | |
| SCHEMBL7368010 | 0.88 | FLT3 (0.46) | SMN1; SMN2RAB9AFLT3KMT2AALDH1A1 | |
| SCHEMBL7370817 | 0.85 | HTT (0.51) | SMN1; SMN2RAB9AFLT3KMT2AMEN1 | |
| SCHEMBL7369592 | 0.81 | NR1H4 (0.50) | SMN1; SMN2FLT3NTRK1NTRK2MAPT | |
| SCHEMBL7366495 | 0.80 | FLT3 (0.45) | SMN1; SMN2RAB9AFLT3KMT2AMEN1 | |
| SCHEMBL7367977 | 0.80 | JAK2 (0.46) | RAB9AFLT3ALDH1A1NTRK1NTRK2 | |
| SCHEMBL7366169 | 0.79 | FLT3 (0.43) | SMN1; SMN2FLT3ALDH1A1LMNACDK2 | |
| SCHEMBL7368426 | 0.77 | NPC1 (0.54) | RAB9AFLT3KMT2AMEN1NPC1 | |
| SCHEMBL7371977 | 0.77 | NR1H4 (0.46) | SMN1; SMN2FLT3KCNK9 | |
| SCHEMBL7366476 | 0.76 | HPGD (0.49) | SMN1; SMN2RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |