Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | DRD2 | P14416 | 3/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.65 |
| ▸ | HTR7 | P34969 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31207179 | 0.97 | L3MBTL1 (0.67) | L3MBTL1TSHRDRD2HTR1AHTR7 | |
| SCHEMBL7672873 | 0.89 | L3MBTL1 (0.65) | L3MBTL1TSHRDRD2HTR1AHTR7 | |
| SCHEMBL28523079 | 0.89 | HTR1A (0.67) | L3MBTL1TSHRDRD2HTR1AHTR7 | |
| SCHEMBL28907245 | 0.89 | HTR1A (0.67) | L3MBTL1TSHRDRD2HTR1AHTR7 | |
| SCHEMBL7692830 | 0.88 | L3MBTL1 (0.68) | L3MBTL1TSHRDRD2HTR1AHTR7 | |
| SCHEMBL1374039 | 0.88 | HTR1A (0.65) | L3MBTL1TSHRDRD2HTR1AHTR7 | |
| SCHEMBL7666917 | 0.88 | HTR1A (0.65) | L3MBTL1TSHRDRD2HTR1AHTR7 | |
| SCHEMBL1377880 | 0.85 | HTR1A (0.63) | L3MBTL1TSHRDRD2HTR1AHTR7 | |
| SCHEMBL8722757 | 0.84 | DRD2 (0.65) | L3MBTL1TSHRDRD2HTR1AHTR7 | |
| SCHEMBL28972660 | 0.84 | L3MBTL1 (0.70) | L3MBTL1TSHRHTR7ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781126-B1 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON SPA (IT) | 2001-12-12 | — | — | EP | disclosed |
| EP-0781126-A2 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008228-A2 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.P.A. (IT) | 1996-03-21 | — | — | WO | disclosed |