Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.65 |
| ▸ | HTR1A | P08908 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.61 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901177 | 0.99 | HTR1A (0.67) | DRD2HTR1ATSHRAVPR2AVPR1A | |
| SCHEMBL8902187 | 0.99 | HTR1A (0.67) | DRD2HTR1ATSHRAVPR2AVPR1A | |
| SCHEMBL8724506 | 0.99 | HTR1A (0.67) | DRD2HTR1ATSHRAVPR2AVPR1A | |
| SCHEMBL8902002 | 0.90 | KMT2A (0.58) | DRD2HTR1ATSHRAVPR2AVPR1A | |
| SCHEMBL8901810 | 0.86 | MAPT (0.67) | DRD2HTR1ATSHRAVPR2AVPR1A | |
| SCHEMBL8722760 | 0.86 | MAPT (0.67) | DRD2HTR1ATSHRAVPR2AVPR1A | |
| SCHEMBL8723365 | 0.86 | TSHR (0.83) | DRD2HTR1ATSHRL3MBTL1ALDH1A1 | |
| SCHEMBL8722383 | 0.85 | HTR1A (0.58) | DRD2HTR1AAVPR2AVPR1AALDH1A1 | |
| SCHEMBL1374039 | 0.85 | HTR1A (0.65) | DRD2HTR1ATSHRL3MBTL1ALDH1A1 | |
| SCHEMBL7367526 | 0.84 | L3MBTL1 (0.67) | DRD2HTR1ATSHRL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042692-A1 | PIPERAZINES DERIVED FROM CYCLIC AMINES, PREPARATION AND APPLICATION THEREOF AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 1998-10-01 | — | — | WO | disclosed |