Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.45 |
| ▸ | TUBB | P07437 | 2/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726919 | 0.91 | MAPT (0.58) | MAPTTDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL8484355 | 0.85 | HTT (0.54) | MAPTTDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL4823325 | 0.84 | TUBB1 (0.59) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10589919 | 0.82 | KMT2A (0.50) | MAPTTDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL8320950 | 0.82 | MCL1 (0.51) | MAPTTDP1PTPN1TUBB1KDM4E | |
| SCHEMBL30069060 | 0.81 | ALDH1A1 (0.59) | MAPTTDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL1421887 | 0.81 | ALDH1A1 (0.59) | MAPTTDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL5709936 | 0.80 | NPC1 (0.56) | MAPTTDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL30374830 | 0.80 | NPC1 (0.56) | MAPTTDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL2137968 | 0.79 | MAPT (0.58) | MAPTALDH1A1KMT2ATUBB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888052-A4 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP (US) | 2002-05-22 | — | — | EP | disclosed |
| EP-0888052-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORPORATION (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034482-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP. (US) | 1997-09-25 | — | — | WO | disclosed |