Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HMGCR | P04035 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726919 | 0.86 | MAPT (0.58) | TUBB1MAPTTDP1NPC1RAB9A | |
| SCHEMBL30374830 | 0.86 | NPC1 (0.56) | TUBB1MAPTTDP1HPGDLMNA | |
| SCHEMBL5709936 | 0.86 | NPC1 (0.56) | TUBB1MAPTTDP1HPGDLMNA | |
| SCHEMBL7367549 | 0.85 | MAPT (0.50) | TUBB1MAPTTDP1KDM4EHSD17B10 | |
| SCHEMBL7336340 | 0.81 | LMNA (0.58) | HTTTUBB1MAPTTDP1KDM4E | |
| SCHEMBL10589919 | 0.78 | KMT2A (0.50) | HTTMAPTTDP1KDM4EHPGD | |
| SCHEMBL8484707 | 0.77 | MAPT (0.63) | HTTTUBB1MAPTTDP1KDM4E | |
| SCHEMBL7340588 | 0.77 | LMNA (0.59) | HTTMAPTHMGCRKDM4EHPGD | |
| SCHEMBL4823325 | 0.77 | TUBB1 (0.59) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27713896 | 0.75 | MAPT (0.76) | TUBB1MAPTTDP1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981774-A | PREPARING 3,5-DI(2,3-EPOXYPROPOXY)-1-HYDROXYXANTHONE BY REACTING 1,3,5-TRIMETHOXYXANTHONE WITH HYDROGEN IODIDE IN PHENOL WHEREBY 1,3,5-TRIHYDROXYXANTHONE IS OBTAINED, REACTING PRODUCT WITH EPICHLOROHYDRIN IN POTASSIUM HYDROXIDE | NATIONAL SCIENCE COUNCIL (TW) | 1999-11-09 | — | — | US | disclosed |
| US-5741813-A | ADMINISTERING SUBSTITUTED XANTHONES | NATIONAL SCIENCE COUNCIL (TW) | 1998-04-21 | — | — | US | disclosed |